PRDM1 / BLIMP1 antibody (mAb)

RRID: AB_2615011
Clone: ROS195
Aliases: PRDI-BF1
Catalog No: 61167 Format: 100 µg ¥5,500 Buy
Catalog No: 61168 Format: 10 µg ¥1,380 Buy

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Antibody Type:
Monoclonal
Isotype:
IgG1
Purification:
Protein G Chromatography
Host:
Mouse
Molecular Weight:
77 and 95 kDa
Reactivity:
Human

Applications

Western Blot Validated Immunoprecipitation Validated Immunohistochemistry Validated

Published Applications

The following applications have been published using this antibody. Unless noted above, Active Motif may not have validated the antibody for use in these applications:

IHC
IP
WB

View publications that use Active Motif products & services here. Enter the product number(s) to see publications & applications that use this antibody.

Immunogen

This PRDM1 / BLIMP1 antibody was raised against full-length recombinant human PRDM1 / BLIMP1 protein.

Buffer

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

Background

PRDM1 / BLIMP1 is a transcriptional repressor that binds to specific target sites in DNA and recruits co-repressors. PRDM1 / BLIMP1 is a master regulator for B cell terminal differentiation, is essential for normal development and immunity and a putative tumor suppressor in diffuse large B cell lymphomas (DLBCLs). PRDM1 / BLIMP1 specifies primordial germ cells through the silencing of the default somatic pathway. PRDM1 / BLIMP1 also acts as a master regulator of intestinal maturation.

Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Guarantee

This product is guaranteed for 12 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • ChIP = ChIP Sequencing;
  • CUT&RUN = Cleavage Under Targets and Release Using Nuclease;
  • CUT&Tag = Cleavage Under Targets and Tagmentation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • NEU = Neutralizing;
  • WB = Western Blotting