FactorPath™ ChIP-Seq Services

map transcription factor binding across the genome

 

FactorPath ChIP-Seq Service Overview

Transcription Factors

Active Motif’s FactorPath™ ChIP-Seq Service can be used to map the binding of transcription factors on a genome-wide scale. Researchers use our FactorPath ChIP-Seq Service for many applications, including identifying the consensus binding motifs of poorly characterized transcription factors and mapping changes in the binding patterns of transcription factors in response to drug treatments.

Let our team of ChIP-Seq experts help run the experiments and do the bioinformatics for you so you can publish faster and in higher impact journals.

The FactorPath ChIP-Seq Service includes:

  • Chromatin preparation and sonication
  • Performing ChIP with a ChIP-validated antibody
  • Generating ChIP-Seq libraries
  • Performing next-generation sequencing
  • Comprehensive bioinformatics and data analysis
  • Delivery of publication-ready figures

To learn more, please submit an Epigenetic Services Information Request. You can also download Active Motif’s Epigenetic Services Brochure.

 

FactorPath ChIP-Seq Service Data

ChIP-Seq data generated by Active Motif Epigenetic Services maps hundreds of MITF binding sites across a 60 million bp region on chromosome 9
Figure 1: FactorPath™ ChIP-Seq maps MITF binding sites on chromosome 9.

ChIP-Seq was performed using chromatin from a human melanoma cell line (2.5 million cells) and a MITF (Microphthalmia-associated Transcription Factor) monoclonal antibody (Catalog No. 39789). ChIP DNA was sequenced on the Illumina GA II and 19 million sequence tags were mapped to identify MITF binding sites across the genome. The image shows hundreds of MITF binding sites across a 60 million bp region on chromosome 9.

 

 

FactorPath ChIP-Seq Service Documents

 

 

 

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Name Cat No. Price  
FactorPath™ ChIP-Seq 25001 Get Quote