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表观遗传 & 染色质
抗体
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- AbFlex® Recombinant Antibodies
- 桥连抗体
- ChIP验证抗体
- ChIP-Seq & ChIP-chip验证抗体
- 染色质修饰蛋白抗体
- DNA甲基化抗体
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- 转录因子抗体
Antibody Labeling
重组蛋白 & 酶
- 重组蛋白
- DNA损伤相关蛋白
- 生长因子
- 核小体
- 组蛋白和修饰组蛋白
- Histone Peptides
- Bromo结构域蛋白
- RNA Methylation
- 组蛋白乙酰转移酶（HATs）和组蛋白去乙酰化酶(HDACs)
- 组蛋白甲基转移酶（(HMTs)）和组蛋白去甲基化酶(HDMs)
- 蛋白激酶
- 转录因子
- 泛素化
蛋白检测和定量
细胞，组织和组蛋白提取物
荧光
样品制备
- 超声产品
- 染色质免疫共沉淀（ChIP）DNA纯化
- 全基因组扩增
- 细胞核 & 细胞质提取
- Cell-Free DNA (cfDNA) Purification Kit
- 蛋白质 & 提取物定量
- RNA Isolation
- 荧光染料标签
- 线粒体分离
- 杜恩斯匀浆器
转染 & 表达
表观遗传 & 染色质
Recombinant Nucleosomes
ReNucs™ are Recombinant Nucleosomes designed to contain specific histone post-translational modifications, amino acid substitutions and other modifications, delivering the most biologically relevant and powerful tools for development of novel drug targets and precision medicine. Developed in our own labs, each recombinant nucleosome is comprised of octamers of designer-modified core histone proteins (H2A, H2B, H3 and H4) bound by DNA. Active Motif currently offers the widest portfolio of pre-assembled Mononucleosome and Polynucleosome proteins available – and as the Epigenetics Experts, we continue to release newly designed ReNucs every month.
All of our recombinant nucleosomes are available in small scale and bulk quantities. For a bulk order quote, contact us.
HMT activity assay comparing recombinant nucleosomes and histone octamers as substrates (click image to enlarge).
Whatever your application, ReNucs™ recombinant nucleosome proteins offer the most biologically relevant substrates when compared to histone proteins alone or synthetic peptides:
- Mononucleosomes and Polynucleosomes available
- Biotinylated nucleosomes for protein-nucleosome interaction studies and pull-down assays
- Post-translational modifications – designed for optimal physiological relevance
- Amino acid mutations – as published, these ReNucs mostly closely mimic naturally occurring nucleosomes in your own experimental design.
- Coming Soon – Quadra-modified ReNucs, including four post-translational modifications in each nucleosome
| Name | Expressed In | Format | Plain Name | Cat No. | Price | |
|---|---|---|---|---|---|---|
| Recombinant Polynucleosomes (H3.1) | E. coli | 20 µg | Recombinant Polynucleosomes (H3.1) | 31466 | ¥3,304.60 | Buy |
| Recombinant Polynucleosomes (H3.3) | E. coli | 20 µg | Recombinant Polynucleosomes (H3.3) | 31468 | ¥3,304.60 | Buy |
| 1 mg | Recombinant Polynucleosomes (H3.3) | 31868 | ¥31,837 | Buy | ||
| Recombinant Mononucleosomes (H3.1) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes (H3.1) - biotinylated | 31467 | ¥3,304.60 | Buy |
| Recombinant Mononucleosomes (H3.3) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes (H3.3) - biotinylated | 31469 | ¥3,304.60 | Buy |
| Recombinant Polynucleosomes H3.3 (K27M) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (K27M) | 31562 | ¥3,304.60 | Buy |
| Recombinant Polynucleosomes H3.3 (G34L) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34L) | 31558 | ¥3,304.60 | Buy |
| 1 mg | Recombinant Polynucleosomes H3.3 (G34L) | 31958 | ¥31,837 | Buy | ||
| Recombinant Polynucleosomes H3.3 (G34R) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34R) | 31559 | ¥3,304.60 | Buy |
| Recombinant Polynucleosomes H3.3 (G34V) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34V) | 31560 | ¥3,304.60 | Buy |
| Recombinant Polynucleosomes H3.3 (G34W) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34W) | 31561 | ¥3,304.60 | Buy |
| 1 mg | Recombinant Polynucleosomes H3.3 (G34W) | 31961 | ¥31,837 | Buy | ||
| Recombinant Polynucleosomes H3.3 (K36M) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (K36M) | 31563 | ¥3,304.60 | Buy |
| 1 mg | Recombinant Polynucleosomes H3.3 (K36M) | 31963 | ¥31,837 | Buy |
