- Custom Services
- Functional Genomics - LightSwitch™
- 基因调控
-
表观遗传 & 染色质
- 染色质组装
-
染色质免疫共沉淀(ChIP)
- ChIP Sonicators
- ChIP validated Antibodies
- ChIP-IT® Express Chromatin Immunoprecipitation Kits
- ChIP-IT High Sensitivity®
- ChIP-IT® FFPE II
- ChIP-IT® PBMC
- enChIP®
- Low Cell ChIP-Seq
- Low Cell ChIP-Seq Optimization Module
- Tag-ChIP-IT®
- TAM-ChIP™
- Specialized ChIP-IT® Kits
- ChIP Accessory Products
- ChIP DNA Purification Kit
- NGS Library Preparation
-
DNA甲基化 & 富集
- DNA Methylation Antibodies & Enzymes
- Bisulfite Conversion Kits & Epigenetic Services
- Methylated DNA Enrichment
- Quantitative DNA Methylation Assays
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Histone Analysis
- Histone Acetyltransferase Activity (HAT)
- Histone Deacetylase Activity (HDAC)
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Histone Modification ELISAs
- Total Histone H3 ELISA
- Histone H3 methylated Lys4 ELISA (H3K4)
- Histone H3 acetyl Lys9 ELISA (H3K9)
- Histone H3 methylated Lys9 ELISA (H3K9)
- Histone H3 acetyl Lys14 ELISA (H3K14)
- Histone H3 acetyl Lys27 ELISA (H3K27)
- Histone H3 methylated Lys27 ELISA (H3K27)
- Histone H3 phospho Ser10 ELISA (H3S10ph)
- Histone H3 phospho Ser28 ELISA (H3S28ph)
- Histone Peptide Array
- Histone Purification
- Recombinant Histones
- 核小体
- 激活剂 / 抑制剂
- 抗体
- Antibody Labeling
- 重组蛋白 & 酶
- 蛋白检测和定量
- 细胞,组织和组蛋白提取物
- 荧光
- 样品制备
- 转染 & 表达
- 生物信息学
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(871)
Antibodies
- Antibody Type
- Application
- Isotype
- Reactivity
- Modification
- Purification
- Host
- Product Category
- Histone Products
- New Products
- Sample Available
- Antibody Category
-
Research Area
- (464) Chromatin & Histones
- (426) Transcription
- (179) Methylation
- (103) Acetylation & Deacetylation
- (101) Phosphorylation
- (78) Cell Cycle
- (71) DNA Damage & Repair
- (68) Cell Signaling
- (43) Apoptosis
- (21) Nuclear Receptors
- (18) Fluorescence
- (6) Oxidative Stress
- (4) Post Transcription
- (3) Immunoprecipitation
- (1) ELISAs
- (1) SUMOylation
- (1) Ubiquitination
- More
-
(99)
Extracts
- Extract Type
- Extract Species
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Treatment
- (62) Untreated
- (6) TPA
- (3) IL-6
- (2) Forskolin
- (2) H2O2
- (2) Serum
- (2) TNF-α
- (2) TPA + CI
- (1) Acetaldehyde
- (1) Anacardic acid
- (1) Anisomycin
- (1) CoCl2
- (1) Colcemid
- (1) EGF
- (1) Estradiol
- (1) Etoposide
- (1) Heat shock
- (1) Hypoxia
- (1) IFNγ
- (1) IL-1α
- (1) PHA
- (1) Paclitaxel
- (1) Prolactin
- (1) Retinoic acid
- (1) Sodium butyrate
- (1) Testosterone
- More
-
Cell Line / Tissue
- (18) HeLa
- (7) Hep G2
- (6) Jurkat
- (4) MCF-7
- (4) PC-12
- (3) COS-7
- (3) NIH/3T3
- (3) U-937
- (3) WI-38
- (2) A-431
- (2) C2C12
- (2) F9
- (2) K-562
- (2) LNCaP
- (2) Nb2
- (2) SL-2
- (2) T-47D
- (2) THP-1
- (1) 293
- (1) 3T3-L1
- (1) CCRM-CEM
- (1) Caco-2
- (1) DU 145
- (1) HL-60
- (1) HT-29
- (1) Human Heart
- (1) Human Liver
- (1) Human Lung
- (1) JEG-3
- (1) KG-1
- (1) LoVo
- (1) MDA-MB-231
- (1) MG-63
- (1) MIA PaCa-2
- (1) Mouse Brain
- (1) NIH:OVCAR-3
- (1) P19
- (1) PANC-1
- (1) PC-03
- (1) Raji
- (1) Rat Brain
- (1) Rat Liver
- (1) SK-N-BE
- (1) SW48
- (1) Saos-2
- (1) U-87
- (1) Y-79
- (1) ZR-75-1
- More
- Research Area
- Histone Products
- Modification
- (25) Fluorescent Dyes
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(326)
Kits
- New Products
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Product Category
- (94) Chromatin Immunoprecipitation
- (48) Phospho-protein Detection
- (44) Transcription Factor ELISAs
- (42) Sample Preparation
- (25) Epigenetic Services
- (14) DNA Methylation
- (14) Histone ELISAs
- (10) Gelshift / Supershift
- (8) Histone Assays
- (7) Antibody Labeling
- (4) Co-Immunoprecipitation
- (4) Immunofluorescence
- (3) Histone Array
- (2) Chromatin Assembly
- (2) Mitosis Assays
- (1) Nitric Oxide Assays
- (1) Nucleosomes
- (1) Protein Delivery
- (1) Ras GTPase
- (1) miRNA Target Validation
- More
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Research Area
- (176) Chromatin & Histones
- (114) Transcription
- (102) ELISAs
- (100) Immunoprecipitation
- (93) Accessories
- (78) Sample Preparation
- (77) Phosphorylation
- (60) Cell Signaling
- (48) Methylation
- (23) Cell Cycle
- (20) Apoptosis
- (16) Acetylation & Deacetylation
- (15) Sonication
- (10) DNA Damage & Repair
- (8) Fluorescence
- (3) Nuclear Receptors
- (3) Oxidative Stress
- (2) Gene Regulation
- (1) Clinical Research
- (1) DNA Methylation
- (1) Histone Post Translational Modifications
- (1) Post Transcription
- More
- Histone Products
- Modification
- Product Class
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(599)
Recombinant Proteins
- New Products
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Protein Category
- (201) Histone
- (158) Transcription
- (57) Bromodomain
- (55) Histone Methyltransferase (HMT)
- (25) Kinase
- (24) Histone Deacetylase (HDAC)
- (20) Histone Demethylase (HDM)
- (18) DNA Damage
- (16) Nuclear Receptor
- (10) Histone Acetyltransferase (HAT)
- (9) DNA Methyltransferase (DNMT)
- (5) Cytosine Oxygenase (TET)
- (1) Glucosyltransferase
- (1) Neddylation
- (1) Ubiquitination
- More
- Expressed In
- Protein Species
- Modification
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Research Area
- (385) Chromatin & Histones
- (239) Methylation
- (201) Transcription
- (127) Acetylation & Deacetylation
- (43) Phosphorylation
- (39) Cell Signaling
- (25) Post Transcription
- (21) Cell Cycle
- (16) Nuclear Receptors
- (14) DNA Damage & Repair
- (12) Oxidative Stress
- (9) Apoptosis
- (3) Ubiquitination
- (2) Sample Preparation
- More
- Histone Products
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(149)
Reporter Assays
- LightSwitch™ Collections
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Product Category
- (92) Synthetic Response Elements
- (11) Pathway Biomarker Sets
- (8) LightSwitch™ 3´UTR Controls
- (8) LightSwitch™ Promoter Controls
- (8) LightSwitch™ Reporter Collections
- (8) Stable Reporter Cell Lines
- (4) LightSwitch™ Empty Vectors
- (3) Gene Regulation Services
- (3) Transfection Reagents
- (2) miRNA Mimics and Inhibitors
- (1) LightSwitch™ Assay Kits
- (1) Synthetic miRNA Targets
- More
- Research Area
- miRNA Products
- Type of Control
- (59) Small Molecules
表观遗传 & 染色质
Recombinant Nucleosomes

- 表观遗传 & 染色质
- »
- 核小体
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- Recombinant Nucleosomes
AVAILABLE PRODUCTS
RELATED PRODUCTS
ReNucs™ are Recombinant Nucleosomes designed to contain specific histone post-translational modifications, amino acid substitutions and other modifications, delivering the most biologically relevant and powerful tools for development of novel drug targets and precision medicine. Developed in our own labs, each recombinant nucleosome is comprised of octamers of designer-modified core histone proteins (H2A, H2B, H3 and H4) bound by DNA. Active Motif currently offers the widest portfolio of pre-assembled Mononucleosome and Polynucleosome proteins available – and as the Epigenetics Experts, we continue to release newly designed ReNucs every month.

All of our recombinant nucleosomes are available in small scale and bulk quantities. For a bulk order quote, contact us.

HMT activity assay comparing recombinant nucleosomes and histone octamers as substrates (click image to enlarge).
Whatever your application, ReNucs™ recombinant nucleosome proteins offer the most biologically relevant substrates when compared to histone proteins alone or synthetic peptides:
- Mononucleosomes and Polynucleosomes available
- Biotinylated nucleosomes for protein-nucleosome interaction studies and pull-down assays
- Post-translational modifications – designed for optimal physiological relevance
- Amino acid mutations – as published, these ReNucs mostly closely mimic naturally occurring nucleosomes in your own experimental design.
- Coming Soon – Quadra-modified ReNucs, including four post-translational modifications in each nucleosome
Name | Expressed In | Format | Plain Name | Cat No. | Price | |
---|---|---|---|---|---|---|
Recombinant Polynucleosomes (H3.1) | E. coli | 20 µg | Recombinant Polynucleosomes (H3.1) | 31466 | ¥3,304.60 | Buy |
Recombinant Polynucleosomes (H3.3) | E. coli | 20 µg | Recombinant Polynucleosomes (H3.3) | 31468 | ¥3,304.60 | Buy |
1 mg | Recombinant Polynucleosomes (H3.3) | 31868 | ¥31,837 | Buy | ||
Recombinant Mononucleosomes (H3.1) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes (H3.1) - biotinylated | 31467 | ¥3,304.60 | Buy |
Recombinant Mononucleosomes (H3.3) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes (H3.3) - biotinylated | 31469 | ¥3,304.60 | Buy |
Recombinant Polynucleosomes H3.3 (K27M) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (K27M) | 31562 | ¥3,304.60 | Buy |
Recombinant Polynucleosomes H3.3 (G34L) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34L) | 31558 | ¥3,304.60 | Buy |
1 mg | Recombinant Polynucleosomes H3.3 (G34L) | 31958 | ¥31,837 | Buy | ||
Recombinant Polynucleosomes H3.3 (G34R) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34R) | 31559 | ¥3,304.60 | Buy |
Recombinant Polynucleosomes H3.3 (G34V) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34V) | 31560 | ¥3,304.60 | Buy |
Recombinant Polynucleosomes H3.3 (G34W) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34W) | 31561 | ¥3,304.60 | Buy |
1 mg | Recombinant Polynucleosomes H3.3 (G34W) | 31961 | ¥31,837 | Buy | ||
Recombinant Polynucleosomes H3.3 (K36M) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (K36M) | 31563 | ¥3,304.60 | Buy |
1 mg | Recombinant Polynucleosomes H3.3 (K36M) | 31963 | ¥31,837 | Buy |