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ReNucs™ are Recombinant Nucleosomes designed to contain specific histone post-translational modifications, amino acid substitutions and other modifications, delivering the most biologically relevant and powerful tools for development of novel drug targets and precision medicine. Developed in our own labs, each recombinant nucleosome is comprised of octamers of designer-modified core histone proteins (H2A, H2B, H3 and H4) bound by DNA. Active Motif currently offers the widest portfolio of pre-assembled Mononucleosome and Polynucleosome proteins available – and as the Epigenetics Experts, we continue to release newly designed ReNucs every month. |
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All of our recombinant nucleosomes are available in small scale and bulk quantities. For a bulk order quote, contact us.
View our flyer, for a complete listing of Recombinant Nucleosomes,
Mononucleosomes, Polynucleosomes, and related proteins.
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Whatever your application, ReNucs™ recombinant nucleosome proteins offer the most biologically relevant substrates when compared to histone proteins alone or synthetic peptides:
- Mononucleosomes and Polynucleosomes available
- Biotinylated nucleosomes for protein-nucleosome interaction studies and pull-down assays
- Post-translational modifications – designed for optimal physiological relevance
- Amino acid mutations – as published, these ReNucs mostly closely mimic naturally occurring nucleosomes in your own experimental design.
- Coming Soon – Quadra-modified ReNucs, including four post-translational modifications in each nucleosome
| Name | Expressed In | Format | Plain Name | Cat No. | Price | |
|---|---|---|---|---|---|---|
| Recombinant Polynucleosomes (H3.1) | E. coli | 20 µg | Recombinant Polynucleosomes (H3.1) | 31466 | ¥3,304.60 | Buy Now |
| Recombinant Polynucleosomes (H3.3) | E. coli | 20 µg | Recombinant Polynucleosomes (H3.3) | 31468 | ¥3,304.60 | Buy Now |
| 1 mg | Recombinant Polynucleosomes (H3.3) | 31868 | ¥31,837 | Buy Now | ||
| Recombinant Mononucleosomes (H3.1) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes (H3.1) - biotinylated | 31467 | ¥3,304.60 | Buy Now |
| Recombinant Mononucleosomes (H3.3) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes (H3.3) - biotinylated | 31469 | ¥3,304.60 | Buy Now |
| Recombinant Polynucleosomes H3.3 (K27M) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (K27M) | 31562 | ¥3,304.60 | Buy Now |
| Recombinant Polynucleosomes H3.3 (G34L) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34L) | 31558 | ¥3,304.60 | Buy Now |
| 1 mg | Recombinant Polynucleosomes H3.3 (G34L) | 31958 | ¥31,837 | Buy Now | ||
| Recombinant Polynucleosomes H3.3 (G34R) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34R) | 31559 | ¥3,304.60 | Buy Now |
| Recombinant Polynucleosomes H3.3 (G34V) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34V) | 31560 | ¥3,304.60 | Buy Now |
| Recombinant Polynucleosomes H3.3 (G34W) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (G34W) | 31561 | ¥3,304.60 | Buy Now |
| 1 mg | Recombinant Polynucleosomes H3.3 (G34W) | 31961 | ¥31,837 | Buy Now | ||
| Recombinant Polynucleosomes H3.3 (K36M) | E. coli | 20 µg | Recombinant Polynucleosomes H3.3 (K36M) | 31563 | ¥3,304.60 | Buy Now |
| 1 mg | Recombinant Polynucleosomes H3.3 (K36M) | 31963 | ¥31,837 | Buy Now | ||
| Recombinant Mononucleosomes (H2A.Bbd) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes (H2A.Bbd) - biotinylated | 31556 | ¥3,506.10 | Buy Now |
| Recombinant Mononucleosomes (TH2B) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes (TH2B) - biotinylated | 31557 | ¥3,506.10 | Buy Now |
| Recombinant Mononucleosomes (H2A.X) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes (H2A.X) - biotinylated | 31582 | ¥3,506.10 | Buy Now |
| Recombinant Mononucleosomes (H2A.Z) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes (H2A.Z) - biotinylated | 31583 | ¥3,506.10 | Buy Now |
| Recombinant Mononucleosomes H3K4me3 (EPL) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes H3K4me3 (EPL) - biotinylated | 31584 | ¥3,586.70 | Buy Now |
| Recombinant Mononucleosomes H3K4me1 (EPL) - biotinylated | E. coli | 20 µg | Recombinant Mononucleosomes H3K4me1 (EPL) - biotinylated | 31585 | ¥3,586.70 | Buy Now |
| Recombinant Mononucleosomes H3K9me3 (EPL) | E. coli | 20 µg | Recombinant Mononucleosomes H3K9me3 (EPL) | 31586 | ¥3,425.50 | Buy Now |
| Recombinant Histone Octamer (H3.1) | E. coli | 100 µg | Recombinant Histone Octamer (H3.1) | 31470 | ¥3,304.60 | Buy Now |
| 1 mg | Recombinant Histone Octamer (H3.1) | 31870 | ¥25,792 | Buy Now | ||
| Recombinant Histone Octamer (H3.1) - biotinylated | E. coli | 50 µg | Recombinant Histone Octamer (H3.1) - biotinylated | 31471 | ¥3,828.50 | Buy Now |
| 1 mg | Recombinant Histone Octamer (H3.1) - biotinylated | 31871 | ¥28,210 | Buy Now | ||
| Recombinant Histone Octamer (H3.3) | E. coli | 100 µg | Recombinant Histone Octamer (H3.3) | 31472 | ¥3,304.60 | Buy Now |
| 1 mg | Recombinant Histone Octamer (H3.3) | 31872 | ¥25,792 | Buy Now | ||
| Recombinant Histone Octamer (H3.3) - biotinylated | E. coli | 50 µg | Recombinant Histone Octamer (H3.3) - biotinylated | 31473 | ¥3,828.50 | Buy Now |
| 1 mg | Recombinant Histone Octamer (H3.3) - biotinylated | 31773 | ¥28,210 | Buy Now | ||
| Recombinant Mononucleosomes H3K27ac - biotin | E. coli / Synthetic | 10 µg | Recombinant Mononucleosomes H3K27ac - biotin | 81002 | ¥3,304.60 | Buy Now |
| Recombinant Mononucleosomes H3K4me1/H3K27ac - biotin | E. coli / Synthetic | 10 µg | Recombinant Mononucleosomes H3K4me1/H3K27ac - biotin | 81003 | ¥3,344.90 | Buy Now |
| Recombinant Mononucleosomes H3K4me3/H3K27ac - biotin | E. coli / Synthetic | 10 µg | Recombinant Mononucleosomes H3K4me3/H3K27ac - biotin | 81004 | ¥3,344.90 | Buy Now |
| Recombinant Mononucleosomes H3K4me3/H3K27me3 - biotin | E. coli / Synthetic | 10 µg | Recombinant Mononucleosomes H3K4me3/H3K27me3 - biotin | 81005 | ¥3,344.90 | Buy Now |
| Recombinant Mononucleosomes (H3.1) | E. coli | 50 µg | Recombinant Mononucleosomes (H3.1) | 81070 | ¥3,264.30 | Buy Now |
| 1 mg | Recombinant Mononucleosomes (H3.1) | 81770 | ¥32,240 | Buy Now | ||
| Recombinant Mononucleosomes (H3.3) | E. coli | 50 µg | Recombinant Mononucleosomes (H3.3) | 81071 | ¥3,264.30 | Buy Now |
| 1 mg | Recombinant Mononucleosomes (H3.3) | 81771 | ¥32,240 | Buy Now | ||
| Recombinant Mononucleosomes H3K36me3 (MLA) - biotin | E. coli | 20 µg | Recombinant Mononucleosomes H3K36me3 (MLA) - biotin | 81076 | ¥3,385.20 | Buy Now |
| 1 mg | Recombinant Mononucleosomes H3K36me3 (MLA) - biotin | 81776 | ¥41,912 | Buy Now | ||
| Recombinant Mononucleosomes H4K20me3 (MLA) | E. coli | 20 µg | Recombinant Mononucleosomes H4K20me3 (MLA) | 81080 | ¥3,224 | Buy Now |
| Recombinant Mononucleosomes H4K20me3 (MLA) - biotin | E. coli | 20 µg | Recombinant Mononucleosomes H4K20me3 (MLA) - biotin | 81081 | ¥3,385.20 | Buy Now |
| 1 mg | Recombinant Mononucleosomes H4K20me3 (MLA) - biotin | 81781 | ¥41,912 | Buy Now | ||
| Recombinant Mononucleosomes (H2A.Z) | E. coli | 50 µg | Recombinant Mononucleosomes (H2A.Z) | 81072 | ¥3,264.30 | Buy Now |
| Recombinant Mononucleosomes H3K4me2 (EPL) | E. coli | 20 µg | Recombinant Mononucleosomes H3K4me2 (EPL) | 81073 | ¥3,344.90 | Buy Now |
| Recombinant Mononucleosomes H3K4me2 (EPL) - biotin | E. coli | 20 µg | Recombinant Mononucleosomes H3K4me2 (EPL) - biotin | 81074 | ¥3,586.70 | Buy Now |
| Recombinant Mononucleosomes H3K9ac (EPL) | E. coli | 20 µg | Recombinant Mononucleosomes H3K9ac (EPL) | 81075 | ¥3,344.90 | Buy Now |
| Recombinant Mononucleosomes H3K27ac | E. coli / Synthetic | 10 µg | Recombinant Mononucleosomes H3K27ac | 81077 | ¥3,264.30 | Buy Now |
| Recombinant Mononucleosomes H3K36me3 (MLA) | E. coli | 20 µg | Recombinant Mononucleosomes H3K36me3 (MLA) | 81116 | ¥3,224 | Buy Now |
| 1 mg | Recombinant Mononucleosomes H3K36me3 (MLA) | 81816 | ¥35,867 | Buy Now |
