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Active Motif provides a variety of kits designed for detection and enrichment of DNA fragments containing methylated (5mC) or hydroxymethylated (5hmC) DNA. The resulting enriched DNA can be used in downstream applications, such as real-time PCR analysis, bisulfite conversion, or library prep and sequencing.
Using a His-tagged MBDb2 protein this kit selectively captures DNA fragments containing methylated CpGs from as little as 1 ng of fragmented DNA.
Based on 5hmC-Seal technology, this kit uses chemical labeling of 5hmC residues for highly specific and sensitive capture of DNA fragments containing 5hmC.
Using a 5mC specific antibody the MeDIP Kit provides everything required to perform immunoprecipitation on as little as 100 ng fragmented ssDNA.
Using a 5hmC specific antibody the hMeDIP Kit provides everything required to perform immunoprecipitation on as little as 100 ng fragmented dsDNA.
