Histone Acetylation (HAT & HDAC)

epigenetic modulators of HATs & HDACs

Histone acetylation is a reversible reaction that occurs on the lysine residues of histone tails. Histone acetyltransferases (HATs) catalyze the transfer of an acetyl group from acetyl coenzyme A, while histone deacetylases (HDACs) perform the antagonistic action of removing the acetyl group. Histone acetylation plays an important role in the modulation of chromatin condensation and transcriptional regulation.

Active Motif also offers several small molecule inhibitors to study the effect of changes in HAT and HDAC activity.

 
Name Appl. Format Cat No. Price  
Apicidin HDAC Inhibitor 5 mg 14040 ¥3,840 Add to Cart
1 mg 14041 ¥1,110 Add to Cart
BML-210 HDAC Inhibitor 25 mg 14048 ¥3,580 Add to Cart
5 mg 14049 ¥980 Add to Cart
C646 p300/CBP Inhibitor 25 mg 14052 ¥3,190 Add to Cart
5 mg 14053 ¥910 Add to Cart
CI-994 HDAC Inhibitor 25 mg 14092 ¥4,230 Add to Cart
5 mg 14093 ¥1,240 Add to Cart
CPTH2 Gcn5P Inhibitor 25 mg 14094 ¥4,230 Add to Cart
5 mg 14095 ¥1,240 Add to Cart
CTPB p300 Activator 25 mg 14064 ¥2,800 Add to Cart
5 mg 14065 ¥850 Add to Cart
CUDC-101 HDAC and Receptor Tyrosine Kinase Inhibitor 25 mg 14060 ¥6,500 Add to Cart
5 mg 14061 ¥1,760 Add to Cart
Embelin PCAF Inhibitor 50 mg 14118 ¥3,580 Add to Cart
10 mg 14119 ¥850 Add to Cart
Garcinol p300/pCAF Inhbitor 50 mg 14076 ¥5,010 Add to Cart
10 mg 14077 ¥1,240 Add to Cart
HPA (Hexyl-4-pentynoic acid) HDAC Inhibitor 50 mg 14034 ¥1,560 Add to Cart
10 mg 14035 ¥720 Add to Cart