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Histone acetylation is a reversible reaction that occurs on the lysine residues of histone tails. Histone acetyltransferases (HATs) catalyze the transfer of an acetyl group from acetyl coenzyme A, while histone deacetylases (HDACs) perform the antagonistic action of removing the acetyl group. Histone acetylation plays an important role in the modulation of chromatin condensation and transcriptional regulation.
Active Motif offers several small molecules to study the effect of changes in HAT and HDAC activity.
| Name | Appl. | Format | Cat No. | Price | |
|---|---|---|---|---|---|
| Apicidin | HDAC Inhibitor | 5 mg | 14040 | ¥3,842.50 | Buy Now |
| 1 mg | 14041 | ¥1,087.50 | Buy Now | ||
| BML-210 | HDAC Inhibitor | 25 mg | 14048 | ¥3,480 | Buy Now |
| 5 mg | 14049 | ¥942.50 | Buy Now | ||
| C646 | p300/CBP Inhibitor | 25 mg | 14052 | ¥3,262.50 | Buy Now |
| 5 mg | 14053 | ¥870 | Buy Now | ||
| CI-994 | HDAC Inhibitor | 25 mg | 14092 | ¥4,205 | Buy Now |
| 5 mg | 14093 | ¥1,232.50 | Buy Now | ||
| CPTH2 | Gcn5P Inhibitor | 25 mg | 14094 | ¥4,205 | Buy Now |
| 5 mg | 14095 | ¥1,232.50 | Buy Now | ||
| CTPB | p300 Activator | 25 mg | 14064 | ¥2,900 | Buy Now |
| 5 mg | 14065 | ¥797.50 | Buy Now | ||
| CUDC-101 | HDAC and Receptor Tyrosine Kinase Inhibitor | 25 mg | 14060 | ¥7,250 | Buy Now |
| 5 mg | 14061 | ¥1,812.50 | Buy Now | ||
| Embelin | PCAF Inhibitor | 50 mg | 14118 | ¥3,552.50 | Buy Now |
| 10 mg | 14119 | ¥797.50 | Buy Now | ||
| Garcinol | p300/pCAF Inhbitor | 50 mg | 14076 | ¥4,930 | Buy Now |
| 10 mg | 14077 | ¥1,160 | Buy Now | ||
| HPA (Hexyl-4-pentynoic acid) | HDAC Inhibitor | 50 mg | 14034 | ¥1,595 | Buy Now |
| 10 mg | 14035 | ¥652.50 | Buy Now | ||
| Mocetinostat | HDAC Inhibitor | 25 mg | 14136 | ¥4,350 | Buy Now |
| 5 mg | 14137 | ¥1,160 | Buy Now | ||
| MS-275 | HDAC Inhibitor | 25 mg | 14042 | ¥2,900 | Buy Now |
| 5 mg | 14043 | ¥870 | Buy Now | ||
| Panobinostat | Class I and II HDAC Inhibitor | 25 mg | 14044 | ¥3,842.50 | Buy Now |
| 5 mg | 14045 | ¥1,087.50 | Buy Now | ||
| Romidepsin | HDAC Inhibitor | 5 mg | 14082 | ¥2,900 | Buy Now |
| 1 mg | 14083 | ¥870 | Buy Now | ||
| Sodium phenylbutyrate | HDAC Inhibitor | 5 g | 14032 | ¥1,305 | Buy Now |
| 1 g | 14033 | ¥435 | Buy Now | ||
| TM-2-51 | HDAC8 Activator | 50 mg | 14096 | ¥2,972.50 | Buy Now |
| 10 mg | 14097 | ¥870 | Buy Now | ||
| Trichostatin A | HDAC Inhibitor | 5 mg | 14038 | ¥4,640 | Buy Now |
| 1 mg | 14039 | ¥1,232.50 | Buy Now | ||
| Tubastatin A hydrochloride | HDAC6 Inhibitor | 25 mg | 14084 | ¥5,727.50 | Buy Now |
| 5 mg | 14085 | ¥1,595 | Buy Now | ||
| Valproic Acid, sodium salt | HDAC Inhibitor | 5 g | 14021 | ¥507.50 | Buy Now |
| Vorinostat (SAHA) | HDAC Inhibitor | 50 mg | 14026 | ¥1,812.50 | Buy Now |
| 10 mg | 14027 | ¥725 | Buy Now | ||
| Piceatannol | SIRT1 Activator | 25 mg | 14036 | ¥3,262.50 | Buy Now |
| 5 mg | 14037 | ¥870 | Buy Now |
