- Custom Services
- Functional Genomics - LightSwitch™
- 基因调控
-
表观遗传 & 染色质
- 染色质组装
-
染色质免疫共沉淀(ChIP)
- ChIP Sonicators
- ChIP validated Antibodies
- ChIP-IT® Express Chromatin Immunoprecipitation Kits
- ChIP-IT High Sensitivity®
- ChIP-IT® FFPE II
- ChIP-IT® PBMC
- enChIP®
- Low Cell ChIP-Seq
- Low Cell ChIP-Seq Optimization Module
- Tag-ChIP-IT®
- TAM-ChIP™
- Specialized ChIP-IT® Kits
- ChIP Accessory Products
- ChIP DNA Purification Kit
- NGS Library Preparation
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DNA甲基化 & 富集
- DNA Methylation Antibodies & Enzymes
- Bisulfite Conversion Kits & Epigenetic Services
- Methylated DNA Enrichment
- Quantitative DNA Methylation Assays
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Histone Analysis
- Histone Acetyltransferase Activity (HAT)
- Histone Deacetylase Activity (HDAC)
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Histone Modification ELISAs
- Total Histone H3 ELISA
- Histone H3 methylated Lys4 ELISA (H3K4)
- Histone H3 acetyl Lys9 ELISA (H3K9)
- Histone H3 methylated Lys9 ELISA (H3K9)
- Histone H3 acetyl Lys14 ELISA (H3K14)
- Histone H3 acetyl Lys27 ELISA (H3K27)
- Histone H3 methylated Lys27 ELISA (H3K27)
- Histone H3 phospho Ser10 ELISA (H3S10ph)
- Histone H3 phospho Ser28 ELISA (H3S28ph)
- Histone Peptide Array
- Histone Purification
- Recombinant Histones
- 核小体
- 激活剂 / 抑制剂
- 抗体
- Antibody Labeling
- 重组蛋白 & 酶
- 蛋白检测和定量
- 细胞,组织和组蛋白提取物
- 荧光
- 样品制备
- 转染 & 表达
- 生物信息学
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(871)
Antibodies
- Antibody Type
- Application
- Isotype
- Reactivity
- Modification
- Purification
- Host
- Product Category
- Histone Products
- New Products
- Sample Available
- Antibody Category
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Research Area
- (464) Chromatin & Histones
- (426) Transcription
- (179) Methylation
- (103) Acetylation & Deacetylation
- (101) Phosphorylation
- (78) Cell Cycle
- (71) DNA Damage & Repair
- (68) Cell Signaling
- (43) Apoptosis
- (21) Nuclear Receptors
- (18) Fluorescence
- (6) Oxidative Stress
- (4) Post Transcription
- (3) Immunoprecipitation
- (1) ELISAs
- (1) SUMOylation
- (1) Ubiquitination
- More
-
(99)
Extracts
- Extract Type
- Extract Species
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Treatment
- (62) Untreated
- (6) TPA
- (3) IL-6
- (2) Forskolin
- (2) H2O2
- (2) Serum
- (2) TNF-α
- (2) TPA + CI
- (1) Acetaldehyde
- (1) Anacardic acid
- (1) Anisomycin
- (1) CoCl2
- (1) Colcemid
- (1) EGF
- (1) Estradiol
- (1) Etoposide
- (1) Heat shock
- (1) Hypoxia
- (1) IFNγ
- (1) IL-1α
- (1) PHA
- (1) Paclitaxel
- (1) Prolactin
- (1) Retinoic acid
- (1) Sodium butyrate
- (1) Testosterone
- More
-
Cell Line / Tissue
- (18) HeLa
- (7) Hep G2
- (6) Jurkat
- (4) MCF-7
- (4) PC-12
- (3) COS-7
- (3) NIH/3T3
- (3) U-937
- (3) WI-38
- (2) A-431
- (2) C2C12
- (2) F9
- (2) K-562
- (2) LNCaP
- (2) Nb2
- (2) SL-2
- (2) T-47D
- (2) THP-1
- (1) 293
- (1) 3T3-L1
- (1) CCRM-CEM
- (1) Caco-2
- (1) DU 145
- (1) HL-60
- (1) HT-29
- (1) Human Heart
- (1) Human Liver
- (1) Human Lung
- (1) JEG-3
- (1) KG-1
- (1) LoVo
- (1) MDA-MB-231
- (1) MG-63
- (1) MIA PaCa-2
- (1) Mouse Brain
- (1) NIH:OVCAR-3
- (1) P19
- (1) PANC-1
- (1) PC-03
- (1) Raji
- (1) Rat Brain
- (1) Rat Liver
- (1) SK-N-BE
- (1) SW48
- (1) Saos-2
- (1) U-87
- (1) Y-79
- (1) ZR-75-1
- More
- Research Area
- Histone Products
- Modification
- (25) Fluorescent Dyes
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(326)
Kits
- New Products
-
Product Category
- (94) Chromatin Immunoprecipitation
- (48) Phospho-protein Detection
- (44) Transcription Factor ELISAs
- (42) Sample Preparation
- (25) Epigenetic Services
- (14) DNA Methylation
- (14) Histone ELISAs
- (10) Gelshift / Supershift
- (8) Histone Assays
- (7) Antibody Labeling
- (4) Co-Immunoprecipitation
- (4) Immunofluorescence
- (3) Histone Array
- (2) Chromatin Assembly
- (2) Mitosis Assays
- (1) Nitric Oxide Assays
- (1) Nucleosomes
- (1) Protein Delivery
- (1) Ras GTPase
- (1) miRNA Target Validation
- More
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Research Area
- (176) Chromatin & Histones
- (114) Transcription
- (102) ELISAs
- (100) Immunoprecipitation
- (93) Accessories
- (78) Sample Preparation
- (77) Phosphorylation
- (60) Cell Signaling
- (48) Methylation
- (23) Cell Cycle
- (20) Apoptosis
- (16) Acetylation & Deacetylation
- (15) Sonication
- (10) DNA Damage & Repair
- (8) Fluorescence
- (3) Nuclear Receptors
- (3) Oxidative Stress
- (2) Gene Regulation
- (1) Clinical Research
- (1) DNA Methylation
- (1) Histone Post Translational Modifications
- (1) Post Transcription
- More
- Histone Products
- Modification
- Product Class
-
(599)
Recombinant Proteins
- New Products
-
Protein Category
- (201) Histone
- (158) Transcription
- (57) Bromodomain
- (55) Histone Methyltransferase (HMT)
- (25) Kinase
- (24) Histone Deacetylase (HDAC)
- (20) Histone Demethylase (HDM)
- (18) DNA Damage
- (16) Nuclear Receptor
- (10) Histone Acetyltransferase (HAT)
- (9) DNA Methyltransferase (DNMT)
- (5) Cytosine Oxygenase (TET)
- (1) Glucosyltransferase
- (1) Neddylation
- (1) Ubiquitination
- More
- Expressed In
- Protein Species
- Modification
-
Research Area
- (385) Chromatin & Histones
- (239) Methylation
- (201) Transcription
- (127) Acetylation & Deacetylation
- (43) Phosphorylation
- (39) Cell Signaling
- (25) Post Transcription
- (21) Cell Cycle
- (16) Nuclear Receptors
- (14) DNA Damage & Repair
- (12) Oxidative Stress
- (9) Apoptosis
- (3) Ubiquitination
- (2) Sample Preparation
- More
- Histone Products
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(149)
Reporter Assays
- LightSwitch™ Collections
-
Product Category
- (92) Synthetic Response Elements
- (11) Pathway Biomarker Sets
- (8) LightSwitch™ 3´UTR Controls
- (8) LightSwitch™ Promoter Controls
- (8) LightSwitch™ Reporter Collections
- (8) Stable Reporter Cell Lines
- (4) LightSwitch™ Empty Vectors
- (3) Gene Regulation Services
- (3) Transfection Reagents
- (2) miRNA Mimics and Inhibitors
- (1) LightSwitch™ Assay Kits
- (1) Synthetic miRNA Targets
- More
- Research Area
- miRNA Products
- Type of Control
- (59) Small Molecules
表观遗传 & 染色质
Histone Acetylation (HAT & HDAC)

- 表观遗传 & 染色质
- »
- 激活剂 / 抑制剂
- »
- Histone Acetylation (HAT & HDAC)
AVAILABLE PRODUCTS
Histone acetylation is a reversible reaction that occurs on the lysine residues of histone tails. Histone acetyltransferases (HATs) catalyze the transfer of an acetyl group from acetyl coenzyme A, while histone deacetylases (HDACs) perform the antagonistic action of removing the acetyl group. Histone acetylation plays an important role in the modulation of chromatin condensation and transcriptional regulation.
Active Motif offers several small molecules to study the effect of changes in HAT and HDAC activity.
Name | Appl. | Format | Cat No. | Price | |
---|---|---|---|---|---|
Apicidin | HDAC Inhibitor | 5 mg | 14040 | ¥4,107.50 | Buy |
1 mg | 14041 | ¥1,162.50 | Buy | ||
BML-210 | HDAC Inhibitor | 25 mg | 14048 | ¥3,720 | Buy |
5 mg | 14049 | ¥1,007.50 | Buy | ||
C646 | p300/CBP Inhibitor | 25 mg | 14052 | ¥3,487.50 | Buy |
5 mg | 14053 | ¥930 | Buy | ||
CI-994 | HDAC Inhibitor | 25 mg | 14092 | ¥4,495 | Buy |
5 mg | 14093 | ¥1,317.50 | Buy | ||
CPTH2 | Gcn5P Inhibitor | 25 mg | 14094 | ¥4,495 | Buy |
5 mg | 14095 | ¥1,317.50 | Buy | ||
CTPB | p300 Activator | 25 mg | 14064 | ¥3,100 | Buy |
5 mg | 14065 | ¥852.50 | Buy | ||
CUDC-101 | HDAC and Receptor Tyrosine Kinase Inhibitor | 25 mg | 14060 | ¥7,750 | Buy |
5 mg | 14061 | ¥1,937.50 | Buy | ||
Embelin | PCAF Inhibitor | 50 mg | 14118 | ¥3,797.50 | Buy |
10 mg | 14119 | ¥852.50 | Buy | ||
Garcinol | p300/pCAF Inhbitor | 50 mg | 14076 | ¥5,270 | Buy |
10 mg | 14077 | ¥1,240 | Buy | ||
HPA (Hexyl-4-pentynoic acid) | HDAC Inhibitor | 50 mg | 14034 | ¥1,705 | Buy |
10 mg | 14035 | ¥697.50 | Buy |