Histone Acetylation (HAT & HDAC)

epigenetic modulators of HATs & HDACs

Histone acetylation is a reversible reaction that occurs on the lysine residues of histone tails. Histone acetyltransferases (HATs) catalyze the transfer of an acetyl group from acetyl coenzyme A, while histone deacetylases (HDACs) perform the antagonistic action of removing the acetyl group. Histone acetylation plays an important role in the modulation of chromatin condensation and transcriptional regulation.

Active Motif offers several small molecules to study the effect of changes in HAT and HDAC activity.

 
Name Appl. Format Cat No. Price  
Apicidin HDAC Inhibitor 5 mg 14040 ¥4,107.50 Buy
1 mg 14041 ¥1,162.50 Buy
BML-210 HDAC Inhibitor 25 mg 14048 ¥3,720 Buy
5 mg 14049 ¥1,007.50 Buy
C646 p300/CBP Inhibitor 25 mg 14052 ¥3,487.50 Buy
5 mg 14053 ¥930 Buy
CI-994 HDAC Inhibitor 25 mg 14092 ¥4,495 Buy
5 mg 14093 ¥1,317.50 Buy
CPTH2 Gcn5P Inhibitor 25 mg 14094 ¥4,495 Buy
5 mg 14095 ¥1,317.50 Buy
CTPB p300 Activator 25 mg 14064 ¥3,100 Buy
5 mg 14065 ¥852.50 Buy
CUDC-101 HDAC and Receptor Tyrosine Kinase Inhibitor 25 mg 14060 ¥7,750 Buy
5 mg 14061 ¥1,937.50 Buy
Embelin PCAF Inhibitor 50 mg 14118 ¥3,797.50 Buy
10 mg 14119 ¥852.50 Buy
Garcinol p300/pCAF Inhbitor 50 mg 14076 ¥5,270 Buy
10 mg 14077 ¥1,240 Buy
HPA (Hexyl-4-pentynoic acid) HDAC Inhibitor 50 mg 14034 ¥1,705 Buy
10 mg 14035 ¥697.50 Buy