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Histone acetylation is a reversible reaction that occurs on the lysine residues of histone tails. Histone acetyltransferases (HATs) catalyze the transfer of an acetyl group from acetyl coenzyme A, while histone deacetylases (HDACs) perform the antagonistic action of removing the acetyl group. Histone acetylation plays an important role in the modulation of chromatin condensation and transcriptional regulation.
Active Motif offers several small molecules to study the effect of changes in HAT and HDAC activity.
| Name | Appl. | Format | Cat No. | Price | |
|---|---|---|---|---|---|
| Apicidin | HDAC Inhibitor | 5 mg | 14040 | ¥3,450 | Buy |
| 1 mg | 14041 | ¥980 | Buy | ||
| BML-210 | HDAC Inhibitor | 25 mg | 14048 | ¥3,120 | Buy |
| 5 mg | 14049 | ¥850 | Buy | ||
| C646 | p300/CBP Inhibitor | 25 mg | 14052 | ¥2,930 | Buy |
| 5 mg | 14053 | ¥780 | Buy | ||
| CI-994 | HDAC Inhibitor | 25 mg | 14092 | ¥3,770 | Buy |
| 5 mg | 14093 | ¥1,110 | Buy | ||
| CPTH2 | Gcn5P Inhibitor | 25 mg | 14094 | ¥3,770 | Buy |
| 5 mg | 14095 | ¥1,110 | Buy | ||
| CTPB | p300 Activator | 25 mg | 14064 | ¥2,600 | Buy |
| 5 mg | 14065 | ¥720 | Buy | ||
| CUDC-101 | HDAC and Receptor Tyrosine Kinase Inhibitor | 25 mg | 14060 | ¥6,500 | Buy |
| 5 mg | 14061 | ¥1,630 | Buy | ||
| Embelin | PCAF Inhibitor | 50 mg | 14118 | ¥3,190 | Buy |
| 10 mg | 14119 | ¥720 | Buy | ||
| Garcinol | p300/pCAF Inhbitor | 50 mg | 14076 | ¥4,420 | Buy |
| 10 mg | 14077 | ¥1,040 | Buy | ||
| HPA (Hexyl-4-pentynoic acid) | HDAC Inhibitor | 50 mg | 14034 | ¥1,430 | Buy |
| 10 mg | 14035 | ¥590 | Buy |
