ChIP is a powerful method to study protein-DNA interactions and to investigate the locations of histone modifications across the genome. But ChIP assays take time to master. This video highlights all the ways Active Motif can help you become a ChIP assay expert.
How TransAM® transcription factor activation assays work
TransAM® kits are sensitive, non-radioactive transcription factor ELISA-based assays that facilitate the study of transcription factor activation in mammalian tissue and cell extracts. These optimized assays are available for many different transcription factors. Watch this short video to learn how they work.
This short video provides an overview of the transposase-assisted multiplex ChIP (TAM-ChIP™) technology. TAM-ChIP™ is a robust, one-step method that combines the antibody-directed protein targeting of ChIP with Illumina-compatible next-generation sequencing (NGS) library preparation into a single step.
Active Motif’s EpiShear™ sonication products are ideal for shearing chromatin for use in chromatin immunoprecipitation (ChIP). They were designed to save you time and effort, and include features like a fully programmable digital display to give you the control needed to get the most reproducible results possible.
Active Motif's ready-to-use, pre-washed, and pre-packed Protein G Agarose Columns have been specifically engineered to greatly reduce non-specific binding in ChIP assays. Simply add the ChIP reaction and perform the incubation and wash steps on the column to streamline the process and prevent any loss of material, offering a faster and more reproducible solution to centrifugation and magnetic separation methods.
Identifying Targets of Human microRNAs Using LightSwitchTM 3' UTR GoClones® and miRNA Mimics
This video describes how to use the LightSwitch Luciferase Assay System to identify miRNA targets by co-transfecting individual 3'UTR luciferase reporter constructs and miRNA mimics. This protocol is efficient, reproducible, and amenable to high-throughput analysis.