激活剂 / 抑制剂

表观遗传研究的小分子物质

Active Motif has a collection of small-molecule epigenetic modulators (activators and inhibitors) that target changes to DNA methylation and chromatin remodeling proteins, such as histones. These include targets to DNA Methyltransferases (DNMTs), Histone Acetyltransferases (HATs), Histone Deacetylases (HDACs), Histone Methyltransferases (HMTs), Histone Demethylases (HDMs) and a distinct set of chromatin readers, bromodomains. As epigenetic dysregulation is implicated in many diseases, these modulators represent important tools for researchers in their assay development and drug discovery initiatives.

A list of the available activators and inhibitors for epigenetic research is shown below. Please click on the small molecule name to view complete product information.

 
Name Appl. Format Cat No. Price  
2'-Deoxy-5-fluorocytidine DNMT Inhibitor 250 mg 14108 ¥4,810 Buy
50 mg 14109 ¥1,240 Buy
5-Aza-2'-deoxycytidine (Decitabine) DNMT Inhibitor 50 mg 14100 ¥5,010 Buy
10 mg 14101 ¥1,370 Buy
5-Azacytidine DNMT Inhibitor 250 mg 14102 ¥1,110 Buy
50 mg 14103 ¥330 Buy
6-Thioguanine DNMT Inhibitor 1 g 14126 ¥1,630 Buy
100 mg 14127 ¥460 Buy
AK-7 SIRT2 Inhibitor 25 mg 14054 ¥3,380 Buy
5 mg 14055 ¥850 Buy
Apicidin HDAC Inhibitor 5 mg 14040 ¥3,450 Buy
1 mg 14041 ¥980 Buy
Arecoline hydrobromide ACAT1 Inhibitor 1 g 14132 ¥1,110 Buy
250 mg 14133 ¥460 Buy
AS-8351 KDM5B Inhibitor 25 mg 14112 ¥2,600 Buy
5 mg 14113 ¥650 Buy
BIX-01294 G9a/GLP Inhibitor 25 mg 14072 ¥5,850 Buy
5 mg 14073 ¥1,300 Buy
BML-210 HDAC Inhibitor 25 mg 14048 ¥3,120 Buy
5 mg 14049 ¥850 Buy