激活剂 / 抑制剂

表观遗传研究的小分子物质

Active Motif has a collection of small-molecule epigenetic modulators (activators and inhibitors) that target changes to DNA methylation and chromatin remodeling proteins, such as histones. These include targets to DNA Methyltransferases (DNMTs), Histone Acetyltransferases (HATs), Histone Deacetylases (HDACs), Histone Methyltransferases (HMTs), Histone Demethylases (HDMs) and a distinct set of chromatin readers, bromodomains. As epigenetic dysregulation is implicated in many diseases, these modulators represent important tools for researchers in their assay development and drug discovery initiatives.

A list of the available activators and inhibitors for epigenetic research is shown below. Please click on the small molecule name to view complete product information.

 
Name Appl. Format Cat No. Price  
2'-Deoxy-5-fluorocytidine DNMT Inhibitor 250 mg 14108 ¥5,735 Buy
50 mg 14109 ¥1,472.50 Buy
5-Aza-2’-deoxycytidine (Decitabine) DNMT Inhibitor 50 mg 14100 ¥5,967.50 Buy
10 mg 14101 ¥1,627.50 Buy
5-Azacytidine DNMT Inhibitor 250 mg 14102 ¥1,317.50 Buy
50 mg 14103 ¥387.50 Buy
6-Thioguanine DNMT Inhibitor 1 g 14126 ¥1,937.50 Buy
100 mg 14127 ¥542.50 Buy
AK-7 SIRT2 Inhibitor 25 mg 14054 ¥4,030 Buy
5 mg 14055 ¥1,007.50 Buy
Apicidin HDAC Inhibitor 5 mg 14040 ¥4,107.50 Buy
1 mg 14041 ¥1,162.50 Buy
Arecoline hydrobromide ACAT1 Inhibitor 1 g 14132 ¥1,317.50 Buy
250 mg 14133 ¥542.50 Buy
AS-8351 KDM5B Inhibitor 25 mg 14112 ¥3,100 Buy
5 mg 14113 ¥775 Buy
BIX-01294 G9a/GLP Inhibitor 25 mg 14072 ¥6,975 Buy
5 mg 14073 ¥1,550 Buy
BML-210 HDAC Inhibitor 25 mg 14048 ¥3,720 Buy
5 mg 14049 ¥1,007.50 Buy