激活剂 / 抑制剂

表观遗传研究的小分子物质

Active Motif has a collection of small-molecule epigenetic modulators (activators and inhibitors) that target changes to DNA methylation and chromatin remodeling proteins, such as histones. These include targets to DNA Methyltransferases (DNMTs), Histone Acetyltransferases (HATs), Histone Deacetylases (HDACs), Histone Methyltransferases (HMTs), Histone Demethylases (HDMs) and a distinct set of chromatin readers, bromodomains. As epigenetic dysregulation is implicated in many diseases, these modulators represent important tools for researchers in their assay development and drug discovery initiatives.

A list of the available activators and inhibitors for epigenetic research is shown below. Please click on the small molecule name to view complete product information.

 
Name Appl. Format Cat No. Price  
2'-Deoxy-5-fluorocytidine DNMT Inhibitor 250 mg 14108 ¥5,460 Buy
50 mg 14109 ¥1,370 Buy
5-Aza-2'-deoxycytidine (Decitabine) DNMT Inhibitor 50 mg 14100 ¥5,530 Buy
10 mg 14101 ¥1,560 Buy
5-Azacytidine DNMT Inhibitor 250 mg 14102 ¥1,240 Buy
50 mg 14103 ¥590 Buy
6-Thioguanine DNMT Inhibitor 1 g 14126 ¥1,760 Buy
100 mg 14127 ¥590 Buy
AK-7 SIRT2 Inhibitor 25 mg 14054 ¥3,580 Buy
5 mg 14055 ¥980 Buy
Apicidin HDAC Inhibitor 5 mg 14040 ¥3,840 Buy
1 mg 14041 ¥1,110 Buy
Arecoline hydrobromide ACAT1 Inhibitor 1 g 14132 ¥1,240 Buy
250 mg 14133 ¥590 Buy
AS-8351 KDM5B Inhibitor 25 mg 14112 ¥2,800 Buy
5 mg 14113 ¥850 Buy
Biotin-14-dATP N/A 1 mg 14138 ¥17,160 Buy
200 µg 14139 ¥4,230 Buy
BIX-01294 G9a/GLP Inhibitor 25 mg 14072 ¥6,500 Buy
5 mg 14073 ¥1,560 Buy