Recombinant ALDOA protein

Aliases: Aldolase A, fructose-bisphosphate-A, transcript variant 1
Catalog No: 81304 Format: 50 µg ¥3,600 Buy
Catalog No: 81604 Format: 1 mg ¥24,000 Buy

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Expressed In: E. coli Protein Species: Human

Contents

A representative Technical Data Sheet (TDS) is provided here. Please refer to the lot-specific TDS you will receive with your order for the lot-specific buffer contents and protein concentration.

Background

ALDOA (Aldolase, Fructose-Bisphosphate A) is a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6- bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers.

Application Notes

This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.

Protein Details

Full length human ALDOA protein was expressed in E. coli cells (accession number NP_908930.1) with a C-terminal 6×His tag. The molecular weight of the protein is 40.5 kDa.

 
>Recombinant ALDOA protein gel

Recombinant ALDOA protein gel
10% SDS-PAGE with Coomassie blue staining

MW: 40.5 kDa

Purity: >95%

Storage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Guarantee

This product is guaranteed for 6 months from date of arrival.