Recombinant METTL7B protein

Aliases: Methyltransferase Like 7B, Associated With Lipid Droplets 1
Catalog No: 81208 Format: 20 µg ¥3,920 Buy
Catalog No: 81908 Format: 1 mg ¥32,400 Buy

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Expressed In: Baculovirus Protein Species: Human

Contents

A representative Technical Data Sheet (TDS) is provided here. Please refer to the lot-specific TDS you will receive with your order for the lot-specific buffer contents and protein concentration.

Background

METTL7B (Methyltransferase-Like Protein 7B) was originally identified as a Golgi-associated methyltransferase and is S-adenosylmethionine-dependent. It is associated with a lot of diseases including Muscular Dystrophy, Congenital, Due To Integrin Alpha-7 Deficiency and Supraglottis Cancer. Previous work has shown that RhoBTB1 regulates the integrity of the Golgi complex through METTL7B. RhoBTB1 is required for expression of METTL7B and silencing of either protein leads to fragmentation of the Golgi.

Application Notes

This product was manufactured as described in Protein Details. Where possible, Active Motif has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product.  All available data this product is shown.   

Protein Details

Recombinant METTL7B protein was expressed in a baculovirus expression system as the full length human protein (accession number NP_004681.1) with a C-terminal FLAG tag. The molecular weight of the protein is 29.5 kDa.

 
Recombinant METTL7B protein gel

Recombinant METTL7B protein gel
10% SDS-PAGE gel with Coomassie blue staining
MW: 29.5 kDa
Purity: >65%

Storage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Guarantee

This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.